Medical Writing and Data management

Study subjects will receive one dose of study intervention as assigned at each vaccination visit (Visits 1 and 4) via intramuscular (IM) injection in the upper arm approximately 14 days apart. Study interventions should be administered into the deltoid muscle, preferably of the nondominant arm .

Each subject will be assigned to receive either:

• 35 mcg dose for both vaccinations at day 0 and day 14 (low dose, 15 subjects)
• 70 mcg dose for both vaccinations at day 0 and day 14 (high dose, 15 subjects)
• Placebo for both injections at day 0 and day 14 (Placebo, 15 subjects)